The Shanghai Men's Health Study (SMHS) is a population-based cohort study of 61,480 Chinese men between ages 40 and 74 who lived in eight urban communities in Shanghai at enrollment (2002-2006). Detailed information on dietary and other lifestyle factors was collected at baseline and updated in follow-up surveys. Biological samples (blood, and or urine) were collected from 89% of cohort members. The cohort has been followed up for cancer occurrence and deaths via linkage with the population-based Shanghai Cancer Registry and the Shanghai Vital Statistics Unit, as well as through visits to all living cohort members every 3-4 years. The resources from this study have supported multiple projects that investigate the etiology of cancers and other chronic diseases, such as coronary heart diseases, diabetes, stroke, and hypertension. The SMHS is jointly conducted by the Vanderbilt Epidemiology Center and the Shanghai Cancer Institute.

A detailed description of cohort methodology and characteristics can be found in this paper: Shu XO, Li H, Yang G, Gao J, Cai H, Takata Y, Zheng W, Xiang YB. Cohort Profile: The Shanghai Men's Health Study. Int J Epidemiol. 2015 Jun;44(3):810-8. doi: 10.1093/ije/dyv013. Epub 2015 Mar 2. PMID: 25733578; PMCID: PMC4521127.

Investigators who are interested in using cohort data or/and biological samples are required to register and submit an application

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